Smallpox : Pathogenesis and Pathology Essay -- Disease virus Variola

variola Pathogenesis and Pathologyvariola was eradicated in 1980 by the Center for Disease and control. It is now contained in five labs in the United States and Russia, however there are other labs in the world with smallpox. variola major is created from the virus Variola which inoculates itself through the peel off and into the derma or more commonly from prolong, direct administration to face contact. smallpox incubates for as long as two weeks at which beat it is multiplying in the lymph nodes and wad marrow. The virus is too able to enter the filiation decant and travel through without being harmed by macrophages. The variola virus also causes monkeypox and cowpox however none of these are as large(p) or as fatal as smallpox.Smallpox is transferred through the crease from prolonged face-to-face exposure. It is also transferred by skin inoculated into the derma oft dates in an existing wound. one time a homo is infected with smallpox, the virus incubate s for a period of ten to fourteen days, at which time the human was not infectious. In the brooding period the variola virus multiplies. Once the incubation period ends smallpox infects the respiratory tract which at this time cannot be detected nor provide any symptoms. Next, the virus replicates in the lymph nodes, bone marrow, and spleen. The smallpox virus creates virions which carry the viral DNA from cellphone to cell defend it from the inhospitable conditions of the body. There the infected macrophages and virions infect other macrophages in the dermis thus spreading the virus later causing the pustules on the skin. humiliation and edema follow causing such legions to leave imperishable scars at one time the pustules scab and fall off (Aguayo).The first cells to become actively produced f... ...0/vaccinia_virus.html.Langohr, I. M., G. W. Stevenson, H. L. Thacker, and R. L. Regnery. enormous Lesions of Monkeypox in a Prairie Dog. Veterinary Pathology. 2004. Universi ty of California Davis. 24 July 2007 . mayo Clinic. Smallpox. MayoClinic.Com. 12 Aug. 2005. Infectious Disease. 25 July 2007 .Smallpox. Armed Forces Institute of Pathology,. 1 Jan. 1970. 27 July 2007 .Smallpox Vaccine And Monkeypox. Center for Disease Control. 1 Jan. 1970. 25 July 2007 .Webmd. variola vaccinia Infection, Human. EMedicine.Com. 29 July 2007. WebMD. 23 July 2007 . Smallpox Pathogenesis and Pathology Essay -- Disease virus VariolaSmallpox Pathogenesis and PathologySmallpox was eradicated in 1980 by the Center for Disease and control. It is now contained in five labs in the United States and Russia, however there are other labs in the world with smallpox. Smallpox is created from the virus Variola which inoculates itself through the skin and into the dermis or more commonly from prolonged, direct face to face contact. Smallpox incubates for as long as two weeks at which time it is multiplying in the lymph nodes and bone marrow. The virus is also able to enter the blood stream and travel through without being harmed by macrophages. The variola virus also causes monkeypox and cowpox however none of these are as bad or as fatal as smallpox.Smallpox is transferred through the air from prolonged face-to-face exposure. It is also transferred by skin inoculated into the dermis often in an existing wound. Once a human is infected with smallpox, the virus incubates for a period of ten to fourteen days, at which time the human was not infectious. In the incubation period the variola virus multiplies. Once the incubation period ends smallpox infects the respiratory tract which at this time cannot be detected nor provide any symptoms. Next, the virus replicates in the lymph nodes, bone marrow, and spleen. The smallpox virus creates virions which carry the viral DNA from cell to cell protecting it from the inhospitable conditions of the body. There the infected macrophages and virions infect other macrophages in the dermis thus sprea ding the virus later causing the pustules on the skin. Necrosis and edema follow causing such legions to leave permanent scars once the pustules scab and fall off (Aguayo).The first cells to become actively produced f... ...0/vaccinia_virus.html.Langohr, I. M., G. W. Stevenson, H. L. Thacker, and R. L. Regnery. Extensive Lesions of Monkeypox in a Prairie Dog. Veterinary Pathology. 2004. University of California Davis. 24 July 2007 .Mayo Clinic. Smallpox. MayoClinic.Com. 12 Aug. 2005. Infectious Disease. 25 July 2007 .Smallpox. Armed Forces Institute of Pathology,. 1 Jan. 1970. 27 July 2007 .Smallpox Vaccine And Monkeypox. Center for Disease Control. 1 Jan. 1970. 25 July 2007 .Webmd. Cowpox Infection, Human. EMedicine.Com. 29 July 2007. WebMD. 23 July 2007 .